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Ralph Teller

Maternal Antidepressant use can cause Infant Structural Brain Damage

by Ralph Teller

SSRI use causes children to experience headaches and problems with balance to require surgery

Maternal antidepressant use may be associated with structural brain changes in infants, according to a recent study lead by Rebecca Knickmeyer, PhD. an assistant professor at the University of North Carolina at Chapel Hill.

The study showed that the offspring of mothers who used selective serotonin reuptake inhibitors (SSRI - antidepressants) during pregnancy were significantly more likely to develop Chiari type I brain malformation (CIM).

Some of these defects caused the children to experience headaches and problems with balance severe enough to require surgery.

The most commonly used antidepressant by the mothers in the study was sertraline (Zoloft, Pfizer Inc), followed by fluoxetine and citalopram.

Overall, the study found a striking increase in the brain abnormality CIM in children with prenatal SSRI exposure.

Recently, a doctor group has sought to limit antipsychotics use, including antidepressants, due to harmful side effects in infants, children, adolescents and adults. Hopefully this group will help convince their fellow doctors against the widespread prescription of these dangerous medications. See Doctor Group seeks to Limit Antipsychotics use due to Harmful Side Effects

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Antipsychotics Articles

PublicationMaternal Antidepressant Use Linked to Infant Brain Malformations, Deborah Brauser, Medscape

PublicationRate of Chiari I Malformation in Children of Mothers with Depression with and without Prenatal SSRI Exposure, Rebecca C Knickmeyer, Neuropsychopharmacology

PublicationFive Things Physicians and Patients Should Question, Choosing Wisely, American Psychiatric Association

PublicationAntipsychotics Increase Risk of Type 2 Diabetes in Children and Young Adults, Alba Morales Pozzo, MD; Chief Editor: Stephen Kemp, MD, PhD, Medscape

PublicationImplications of Marked Weight Gain Associated With Antipsychotic Medications in Children and Adolescents , Christopher K. Varley, MD and Jon McClellan, MD, JAMA

Children and adolesents experience substantial antipsychotic medication caused weight gain and adverse metabolic effects, with more than half gaining more than 7% of their total body weight.

PublicationSmoking and Mental Illness: Results From Population Surveys in Australia and the United States , David Lawrence; Francis Mitrou; Stephen R Zubrick, BMC Public Health

PublicationAntidepressants Linked to Increased Risk for Death, Stroke in Postmenopausal Women , Pam Harrison, Department of Community Health Sciences, University of Calgary, Medscape

PublicationWeight Gain in Relation to Major Depression and Antidepressant Medication Use , Patten SB, Medscape Medical News

PublicationAntidepressants May Only Be Effective in Treatment of the Severest Depression , Caroline Cassels, Medscape Medical News

PublicationWhole Diet May Ward Off Depression and Anxiety , Caroline Cassels, Medscape Medical News

PublicationUnintentional Drug Poisoning (overdose) Deaths: A National Epidemic , Bret Stetka, MD, Medscape

PublicationBroad Review of FDA Trials Suggests Antidepressants Only Marginally Better than Placebo, Deborah Brauser, Medscape

PublicationAntidepressant Use Linked with Increased Artherosclerosis Measured by Carotoid IMT, Heartwire, Medscape

PublicationMom's Antidepressant Use Linked to Autism Risk in Children, Psychiatry, Medscape

PublicationMore Evidence Confirms Diet's Link to Mental Health, Caroline Cassels, Psychiatry, Medscape

PublicationTricyclic Antidepressants Linked to Increased Cardiovascular Risk, Megan Brooks, Medscape

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